Polls across six states closed at 7 p.m. EST, including battlegrounds Georgia, Indiana and Kentucky. Polls in other key states including Florida, Pennsylvania and New Jersey closed at 8 p.m. EST.
At least two lower-profile elections with presidential implications were decided after the first major wave of polls closed in the East.
Vermont Sen. Bernie Sanders easily won his third term as he considers another bid for the Democratic presidential nomination. And Massachusetts Sen. Elizabeth Warren, another potential 2020 contender, also won her race.
Health care and immigration were high on voters' minds as they cast ballots in the midterm elections, per a wide-ranging survey by The Associated Press.
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